Reconstruction of a large-sized defect in the upper abdominal wall with a porcine small intestinal submucosa biodegradable membrane in a newborn with Poland syndrome

Kaja Krystyna Gizewska-Kacprzak, Krzysztof Mikulski, Hanna Chojnacka, Elżbieta Gawrych


Severe cases of gastroschisis require advanced and multi-staged surgical techniques to cover the abdominal wall defect enabling a secure covering of the eventrated organs. A biodegradable porcine small intestinal submucosa membrane is an attractive material that demonstrates the benefits of bioabsorbable materials. It has been used in children. There are only a few reports of severe gastroschisis treatment with this material. The aim of this work is to present a rare case of a giant upper abdominal wall defect in a newborn with Poland syndrome, treated surgically with a biodegradable membrane. The treatment protected the child from infection and enabled satisfactory healing. The use of the described material was adjusted to the severe general condition of the patient. The biodegradable porcine small intestinal submucosa membrane is a safe material to cover a largesized abdominal defect in newborns.


abdominal wall defects; porcine submucosa collagen graft; newborn; gastroschisis; biodegradable membrane

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Fischer JD, Chun K, Moores DC, Andrews HG. Gastroschisis: a simple technique for staged silo closure. J Pediatr Surg 1995;30(8):1169-71.

Lin HK, Godiwalla SY, Plamer B, Frimberger D, Yang Q, Madihally SV, et al. Understanding roles of porcine small intestinal submucosa in urinary bladder regeneration: identification of variable regenerative characteristics of small intestinal submucosa. Tissue Eng Part B Rev 2014;20(1):73-83.

Gabriel A, Gollin G. Management of complicated gastroschisis with porcine small intestinal submucosa and negative pressure wound therapy. J Pediatr Surg 2006;41(11):1836-40.

Karpelowsky JS, Thomas G, Shun A. Definitive abdominal wall closure using a porcine intestinal submucosa biodegradable membrane in pediatric transplantation. Pediatr Transplant 2009;13(3):285-9.

Bellows CF, Albo D, Berger DH, Awad SS. Abdominal wall repair using human acellular dermis. Am J Surg 2007;194(2):192-8.

Lantis JC 2nd, Gallivan EK, Hekier R, Connolly R, Schwaitzberg SD, Crombleholme T. A comparison of collagen and PTFE patch repair in a rabbit model of congenital diaphragmatic hernia. J Invest Surg 2000;13(6):319-25.

Drewa T, Sir J, Czajkowski, R, Woźniak A. Scaffold seeded with cells is essential in urothelium regeneration and tissue remodeling in vivo after bladder augmentation using in vitro engineering graft. Transplant Proc 2006;38(1):133-5.

Drewa T, Galazka P, Prokurat A, Wolski Z, Sir J, Wysocka K, et al. Abdominal wall repair using a biodegradable scaffold seeded with cells. J PediatrSurg 2005;40(2):317-21.

Yiyit N, Işıtmangil T, Öksüz S. Clinical analysis of 113 patients with Poland syndrome. Ann Thorac Surg 2015;99(3):999-1004.


Copyright (c) 2021 Kaja Krystyna Gizewska-Kacprzak, Krzysztof Mikulski, Hanna Chojnacka, Elżbieta Gawrych

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