The effect of biological and environmental factors on the concentration of chromium in human bone

Natalia Łanocha-Arendarczyk, Elżbieta Kalisińska, Małgorzata Anna Kaplewska, Halina Budis, Sebastian Sokołowski, Karolina Kot, Danuta Kosik-Bogacka

Abstract


ABSTRACT

Introduction: The aim of this study was to investigate and compare concentrations of chromium (Cr) in the cartilage cortical bone and spongy bone in the femoral head. In addition, we examined how Cr levels were influenced by general biological and environmental factors.

Materials and methods: Material was collected from patients (n = 37) who had undergone hip replacement surgery. Cartilage, and cortical and spongy bone samples were taken from the femoral head, dried to a constant weight, digested in acids, and tested for the Cr concentration by atomic absorption spectrophotometry (ICP-AES).

Results: Chromium concentration in the analyzed bone samples could be arranged in the following descending series: cartilage < cortical bone < spongy bone. We found no effect of sex and age on the bone Cr concentrations. Chromium levels in heavy

industry workers were nearly 30% higher than in those employed in other sectors of the economy. Chromium levels in cortical bones showed a difference between patients smoking fewer than 10 cigarettes per day and those smoking 20 and more per day. The share of game meat, fish and seafood in the diet had no significant effect on Cr levels in the examined samples.

Conclusions: There are many indications that Cr levels in the bone and cartilage of patients who had undergone hip replacement surgery may be associated with environmental and general biological factors. However, definite conclusions require a greater number of studies and a wider scope of research, including a greater geographical range (i.e. involving other Central European countries).


Keywords


chromium; cartilage; cortical and spongy bones; biological and environmental factors

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References


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DOI: https://doi.org/10.21164/pomjlifesci.371

Copyright (c) 2018 Natalia Łanocha-Arendarczyk, Elżbieta Kalisińska, Małgorzata Anna Kaplewska, Halina Budis, Sebastian Sokołowski, Karolina Kot, Danuta Kosik-Bogacka

License URL: https://creativecommons.org/licenses/by-nc-nd/3.0/pl/