Occurrence of anterior and posterior capsule opacification after cataract surgery with implantation of acrylic hydrophobic heparinized lenses in patients with diabetes type 2

Katarzyna Kubasik-Kładna, Marzena Formicka, Ewelina Lachowicz, Radosław Kiedrowicz, Tomasz Pabin, Wojciech Lubiński


Introduction: A high incidence of capsule opacification was found in diabetic patients after cataract surgery. New surgical techniques and intraocular lens (IOL) modifications decrease posterior capsule opacification (PCO) appearance requiring posterior capsulotomy. It can be assumed that cataract surgery with implantation of heparin-surface-modified IOLs reduces the risk of PCO in patients with diabetes.

The aim of the study is assessment of the influence of acrylic hydrophobic heparinized lenses on the frequency and levels of anterior capsule opacification (ACO) and PCO and visual acuity in patients with diabetes mellitus type 2 after uncomplicated cataract surgery.

Materials and methods: Eighteen patients (36 eyes) with diabetes type 2, without retinopathy were involved in the prospective study. Standard cataract surgery was performed with implantation of acrylic hydrophobic heparinized lens (Polylens Y10AS) in 

one eye (study group) and a non-heparinized lens (Alcon SA60AT) in the opposite eye (control group). Three weeks, 6 months, and 1 year after surgery distance best corrected visual acuity (DBCVA) and assessment of ACO and PCO with retroillumination imaging results were obtained and statistically analysed.

Results: In patients with diabetes type 2 during 1 year follow-up (12 months) there were no statistically significant differences in the frequency of ACO and PCO between eyes with implantation of heparinized and non-heparinized lenses. There were no differences in mean DBCVA between groups during all follow-ups.

Conclusions: Our observations in patients with diabetes type 2, did not reveal greater biocompatibility of heparinized lenses compared to non-heparinized lenses.


diabetes mellitus; cataract surgery; comparison of acrylic hydrophobic heparinized and non-heparinized lenses; DBCVA; capsule opacification

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DOI: https://doi.org/10.21164/pomjlifesci.335

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