Glioblastoma multiforme in a patient with common variable immunodeficiency and multiple malignancies – a case report

Authors

  • Michał Larysz Pomorski Uniwersytet Medyczny w Szczecinie, Klinika Neurochirurgii i Neurochirurgii Dziecięcej, ul. Unii Lubelskiej 1, 71-252 Szczecin
  • Rafał Becht Pomorski Uniwersytet Medyczny w Szczecinie, Oddział Kliniczny Onkologii, Chemioterapii i Immunoterapii Nowotworów, ul. Unii Lubelskiej 1, 71-252 Szczecin
  • Michał Falco Pomorski Uniwersytet Medyczny w Szczecinie, Oddział Kliniczny Radioterapii, Zachodniopomorskie Centrum Onkologii, ul. Strzałowska 22, 71-730 Szczecin
  • Przemysław Nawrocki Pomorski Uniwersytet Medyczny w Szczecinie, Katedra i Klinika Neurologii, ul. Unii Lubelskiej 1, 71-252 Szczecin
  • Ireneusz Kojder Pomorski Uniwersytet Medyczny w Szczecinie, Zakład Neurokognitywistyki Stosowanej, ul. Unii Lubelskiej 1, 71-252 Szczecin

DOI:

https://doi.org/10.21164/pomjlifesci.237

Keywords:

common variable immune deficiency, glioblastoma multiforme

Abstract

 case of glioblastoma multiforme in female patient suffering from common variable immune deficiency syndrome is presented. The patient with history of previously treated due to breast carcinoma and ovarian cancer. The patient underwent craniotomy 

twice followed by radiotherapy and chemotherapy with temozolomide and finally died after 11 months.

References

Chapel H, Cunningham-Rundles Ch. Update in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditions. Br J Haematol 2009;145(6):709-27.

Abbott JK, Gelfand EW. Common variable immunodeficiency: diagnosis, management, and treatment. Immunol Allergy Clin North Am 2015;35: 637-58.

Resnick ES, Cunningham-Rundles Ch. The many faces of the clinical picture of common variable immune deficiency. Curr Opin Allergy Clin Immunol 2012;12(6):595-601.

Resnick ES, Moshier EL, Godbold JH, Cunningham-Rundles Ch. Morbidity and mortality in CVID. Blood 2012;119(7):1650-7. doi: 10.1182/blood-2011-09-377945.

López-Rocha E, Rodríguez-Mireles K, Segura-Méndez NH, Yamazaki-Nakashimada MA. Malignancies in adult patients with common variable immunodeficiency. Rev Alerg Mex 2015;62(1):22-7.

Todorovic M, Balint B, Andjelic B, Mihaljevic B. Multiple malignancies in a female patient with common variable immunodeficiency syndrome. Singapore Med J 2014;55(10):e162-4.

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Published

2017-03-15

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