Severe Pneumocysits jirovecii pneumonia in a patient allergic to Biseptol after kidney transplantation
DOI:
https://doi.org/10.21164/pomjlifesci.411Keywords:
kidney transplantation, pneumonia, Pneumocystis, immunosuppressionAbstract
ABSTRACTIntroduction: Pneumocystis jirovecii may cause pneumonia in patients treated with immunosuppression. The clinical course is varied, from mild to severe, similar to acute respiratory distress syndrome with treatment in an intensive care unit.
A case report: In the article we present the case of a 59-year-old female after the third cadaveric kidney transplantation with severe, complicated pneumonia caused by this organism, who was additionally allergic to Co-trimoxazole (Biseptol). We present brief recommendations for prophylaxis and alternative drugs to Biseptol, which can be used in prophylactic treatment in such individuals.
References
Morris A, Wei K, Afshar K, Huang L. Epidemiology and clinical significance of pneumocystis colonization. J Infect Dis 2008;197(1):10S-7S. doi: 10.1086/523814.
Gilroy SA, Bennett NJ. Pneumocystis pneumonia. Semin Respir Crit Care Med 2011;32(6):775S-82S. doi: 10.1055/s-0031-1295725.
Danovitch GM. Handbook of kidney transplantation. Philadelphia: Lippincott Willams & Wilkins; 2001. p. 255.
Chapman JR, Marriott DJ, Chen SC, MacDonald PS. Post-transplant Pneumocystis jirovecii pneumonia – a re-emerged public health problem? Kidney Int 2013;84(2):240S-3S.
Radisic M, Lattes R, Chapman JF, del Carmen Rial M, Guardia O, Seu F, et al. Risk factors for Pneumocystis carinii pneumonia in kidney transplant recipients: a case-control study. Transpl Infect Dis 2003;5(2):84S-93S.
Phipps LM, Chen SC, Kable K, Halliday CL, Firacative C, Meyer W, et al. Nosocomial Pneumocystis jirovecii pneumonia: lessons from a cluster in kidney transplant recipients. Transplantation 2011;92(12):1327S-34S. doi: 10.1097/TP.0b013e3182384b57.
