Contents
Spis treści
7 Profilaktyka infekcyjnego zapalenia wsierdzia w gabinecie stomatologicznym – współczesne poglądy
Prophylaxis of infective endocarditis in dental practice – contemporary views
EDITOR’S CHOICE / WYBÓR REDAKCJI
11 Ocena poziomu jakości życia chorych na hemofilię
The evaluation of the quality of life in patients with haemophilia
ABSTRACT
Introduction: Haemophilia is a genetic disease. Bleeding, pain, temporary or long-term lack of physical activity, and even the risk of disability could have a negative impact on the quality of life.
The aim of the paper is to evaluate the quality of life of patients with haemophilia, and to provide answers to the following questions: 1. What is the quality of life of patients with haemophilia? 2. Which sphere of life is given the highest and which is given the lowest score? 3. Is there a connection between the sociodemographic data, the health situation and the quality of life?
Materials and methods: In total 163 adults diagnosed with haemophilia who are mainly treated at home and living in different parts of Poland were included in the survey. All sociodemographic data were collected using an author-designed questionnaire. The quality of life was measured using the WHOQOL-100 questionnaire proposed by World Health Organization.
Results: All surveyed patients were males diagnosed with haemophilia A, which is consistent with the epidemiology of the disease and the fact that haemophilia A is more frequent in Poland than haemophilia B. Most of the males (144) were diagnosed with severe haemophilia, 18 with moderate and only 6 with mild haemophilia. What is more, 126 (75%) respondents had type C hepatitis.
Conclusions: In the field of 6 life spheres measured with the use of the WHOQOL-100 questionnaire the highest score – 14.66 – was gained in the sphere of spirituality, religion and personal beliefs. The lowest score – 12.99 – was gained in the physical sphere, mostly concerning pain and feelings of discomfort. The outcome of 12.89 was gained in the environmental sphere. After detailed analysis of the researched material there was a conclusion made: 1. A group of men with inborn haemophilia demonstrate an average quality of life, comparable to the level of life of sick people living in other European countries. 2. The researched group give the highest estimate to the spiritual sphere of life, religion and personal beliefs, while the physical and environmental spheres were given the lowest estimate. 3. The degree of seriousness of haemophilia is of core importance when it comes to the level of life. Type C hepatitis and the status of pensioner is also a serious matter.
Keywords: haemophilia; disability; quality of life.
20 Dolegliwości bólowe odcinka lędźwiowo-krzyżowego wynikające
z zaburzenia lordozy lędźwiowej
Lumbosacral ailments resulting from deviation of the lumbar lordosis
Wioletta Jagucka-Mętel, Anna Machoy-Mokrzyńska, Adam Nowicki, Adam Figeland, Ewa Sobolewska
24 Ocena właściwości antyoksydacyjnych liści Ginkgo biloba L. po zakończeniu wegetacji
Anna Nowak, Joanna Zielonka-Brzezicka, Danuta Pechaiko, Magdalena Tkacz, Adam Klimowicz
EDITOR’S CHOICE / WYBÓR REDAKCJI
35 Zespół aktywacji makrofagów w chorobie Stilla u dorosłych – opis przypadku
Macrophage activation syndrome in the course of adult-onset Still’s disease – a case report
Marzena Lewandowska, Marek Brzosko
ABSTRACT
Introduction: Macrophage activation syndrome (MAS) is a rare complication of autoimmune diseases. The background of the diseases is immune system dysfunction. The disease is characterized by varying symptomatology and the different dynamics of accumulation of symptoms.
Case report: A female patient diagnosed with adult-onset Still’s disease was admitted to the hospital because of fever, weakness, skin rash and dyspepsia which had lasted for several days. Diagnostic tests revealed the presence of anti-nuclear antibodies, pancytopenia, hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, elevated activity of liver enzymes, and increased levels of C-reactive protein. The initial treatment with empirical antibiotic therapy and intravenous pulses of methylprednisolone was unsuccessful and provided no improvement. On the basis of bone marrow cytological examination, the diagnosis of MAS was established. The patient was treated with dexamethasone and cyclosporine A with improvement. The patient was followed up in the rheumatology out-patient department for 20 months without the relapse of MAS.
Conclusion: Macrophage activation syndrome is a rare, dangerous complication of autoimmune diseases, requiring rapid diagnosis and aggressive treatment.
Keywords: secondary haemophagocytic syndrome; haemophagocytic lymphohistiocytosis; adult-onset Still’s diseases; dexamethasone; cyclosporine.
Maciej Sikora, Marcin Sielski, Agata Stąpor, Dariusz Chlubek
EDITOR’S CHOICE / WYBÓR REDAKCJI
Michał Larysz, Rafał Becht, Michał Falco, Przemysław Nowacki, Ireneusz Kojder
ABSTRACT
A case of glioblastoma multiforme in female patient suffering from common variable immune deficiency syndrome is presented. The patient with history of previously treated due to breast carcinoma and ovarian cancer. The patient underwent craniotomy twice followed by radiotherapy and chemotherapy with temozolomide and finally died after 11 months.
Keywords: common variable immune deficiency; glioblastoma multiforme.
50 Zastosowanie wybranych bodźców fizykalnych podczas profesjonalnych zabiegów kosmetologicznych. Część I. Prąd galwaniczny jako czynnik wspomagający przezskórny transport substancji aktywnych zawartych w profesjonalnych preparatach kosmetycznych
The use of selected physical factors in professional cosmetology treatments. Part I. Galvanic current as a factor enhancing transdermal transport of active ingredients contained in professional cosmetic products
Jolanta Wesołowska, Iza Iwan-Ziętek, Hanna Mosiejczuk, Ewa Kemicer-Chmielewska, Mariola Marchlewicz
60 Leczenie sanatoryjne gruźlicy płuc
przed rokiem 1854
Spa treatment of pulmonary tuberculosis
before 1854
EDITOR’S CHOICE / WYBÓR REDAKCJI
ABSTRACT
The geographic and climatic conditions of Hołosko Wielkie, a locality near Lviv, are presented at the beginning. The medical and organizational activities of the tuberculosis sanatorium opened in this place in 1909 and expanded in 1911 are analyzed. The development of tuberculosis therapy, especially of its early form, are analyzed with full particulars. The doctors working in the spa and the results of treatment in this medical institution are fully presented.
Keywords: history of pulmonology; history of otorhinolaryngology; history of the south-eastern borderland of the Second Republic of Poland.
69 Ochrona podmiotowości prawnej osób niepełnosprawnych intelektualnie
w stopniu umiarkowanym w prawie polskim
Protection of the legal personality of people with moderate intellectual disability in Polish law
Iwona Radlińska
78 In the upcoming issue…