THROMBOTIC THROMBOCYTOPENIC PURPURA IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS – COMPLICATION OF CONNECTIVE TISSUE DISEASE OR OVERLAP SYNDROME?

Dominika Grzegowska, Anna Masiak, Zenobia Czuszyńska, Marcin Ziętkiewicz, Wojciech Homenda, Michalina Pejska, Zbigniew Zdrojewski

Abstract


Thrombotic thrombocytopenic purpura (TTP) and systemic lupus erythematosus (SLE) are two separate diseases, whose clinical symptoms may be similar. The coexistence of these two diseases is very rare. We present the case report of a 29-year-old female patient with simultaneous diagnosis of TTP and SLE. The purpose of this article is to draw attention to the diagnostic difficulties which may result from the co-existence of both diseases.


Keywords


thrombotic thrombocytopenic purpura; systemic lupus erythematosus; metalloproteinase ADAMTS13; thrombotic microangiopathy; overlap syndrome; plasma exchange (PEX)

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References


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DOI: https://doi.org/10.21164/pomjlifesci.73

Copyright (c) 2015 Dominika Grzegowska, Anna Masiak, Zenobia Czuszyńska, Marcin Ziętkiewicz, Wojciech Homenda, Michalina Pejska, Zbigniew Zdrojewski

License URL: https://creativecommons.org/licenses/by-nc-nd/3.0/pl/