Rodzaje śmierci komórki

Roman Paduch, Maria Klatka, Janusz Klatka

Abstrakt


STRESZCZENIE

Homeostaza w organizmie utrzymywana jest przez wiele procesów, w tym również dzięki zachowywaniu równowagi między pojawianiem się nowych komórek a ich umieraniem. W pracy opisano mechanizm i szlaki apoptotycznej śmierci komórek oraz zjawisko nekrozy i autofagii. Ponadto opisano rzadziej prezentowane typy umierania komórek, a mianowicie katastrofę mitotyczną, onkozę i pyroptozę. Przebieg tych procesów jest zróżnicowany, co podkreślono w pracy, a także związany z jednej strony z utrzymaniem stabilności tkanek w przebiegu procesów fizjologicznych, a z drugiej z indukcją i progresją procesów patologicznych. W pracy starano się przedstawić podstawowe różnice między opisywanymi procesami i ich znaczenie dla organizmu.

Słowa kluczowe


apoptoza; autofagia; katastrofa mitotyczna; nekroza; onkoza; pyroptoza

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Bibliografia


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DOI: http://dx.doi.org/10.21164/pomjlifesci.426

Copyright (c) 2018 Roman Paduch, Maria Klatka, Janusz Klatka

URL licencji: https://creativecommons.org/licenses/by-nc-nd/3.0/pl/